Argentina Road trips

9 curated road trips in Argentina — Ruta 40, Calchaquí Valleys, Che Guevara, Motorcycle Diaries. Mapped stops, distance, duration, best season, and practical route notes.

These 9 routes range from 110 to 5000 km and from 1 to 7 days, across 1 country. Top picks: Ruta 40, Calchaquí Valleys, Che Guevara, Motorcycle Diaries.

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  LegendaryRuta 40Argentina · 5,000 km · 3–4 weeksArgentina's longest highway traces 5,000 km of the jagged Andes from the shores of the South Atlantic at Punta Loyola through Los Glaciares, Bariloche, Mendoza, Salta, and the Bolivian border at La Quiaca, traversing 20 national parks, crossing 18 major rivers, and climbing over 27 mountain passes. One of the most epic drives on the planet.
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  IconicCalchaquí ValleysArgentina · 520 km · 4–6 daysThrough the high-altitude Andes of northwestern Argentina, the world's highest vineyards at Cafayate, the sculpted red rock canyons of Quebrada de Cafayate, pre-Inca ruins at Quilmes, and the colonial splendour of Salta.
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  NotableChe Guevara, Motorcycle DiariesArgentina · 2,446 km · 2–3 weeksIn January 1952, Ernesto "Che" Guevara and Alberto Granado left Buenos Aires on a 1947 Norton 500 named La Ponderosa II, riding the lower part of Argentina to San Carlos de Bariloche before struggling through Chile to Santiago. Though the motorcycle was eventually abandoned, retracing the route from Che's birthplace in Rosario reveals the grazing country, Andean crossings, and political awakening that made the man.
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  NotableIbera Wetlands and EsterosArgentina · 360 km · 2-3 daysThis gentle Corrientes road trip links the provincial capital with Argentina’s vast Iberá Wetlands, trading city streets for quiet estero country, bird-filled marshes, and ranchland horizons. Base yourself in Colonia Carlos Pellegrini for lagoon boat trips, capybara and caiman sightings, and long sunset drives on sandy access roads.
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  IconicPeninsula Valdes and Atlantic PatagoniaArgentina · 850 km · 5-7 daysThis Atlantic Patagonia drive links Puerto Madryn with Península Valdés, Punta Tombo, and the long empty coast toward Rawson and Comodoro Rivadavia. Expect whale cliffs, sea lion colonies, penguin rookeries, and big-sky steppe scenery on paved roads with long, rewarding detours.
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  LegendaryRoute of the Seven LakesArgentina · 110 km · 1–2 daysThe most beautiful short drive in South America, Ruta Nacional 40 and Ruta Provincial 234 through the Andes foothills between Bariloche and San Martín de los Andes, threading through seven glacier-fed Andean lakes of extraordinary blue-green clarity: Nahuel Huapi, Espejo, Correntoso, Escondido, Villarino, Falkner, and Machónico. The Swiss Alps transplanted to Patagonia.
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  IconicTierra del Fuego and Ushuaia LoopArgentina · 240 km · 2-3 daysThis southernmost Argentina loop traces the paved and gravel roads around Ushuaia, the Beagle Channel, and Tierra del Fuego National Park, with alpine bays, peat bogs, lenga forests, and big-open steppe. It’s a compact road trip with classic end-of-the-world scenery and frequent wildlife stops.
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  IconicMendoza Wine Region and Uco ValleyArgentina · 180 km · 2-3 daysA relaxed wine-country loop from Mendoza city through Maipú, Luján de Cuyo, and the wide-open Uco Valley. Drive between olive groves, vineyard estates, and snow-backed Andes views, stopping for Malbec tastings, winery lunches, and sunset light over Tunuyán and Tupungato.
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  IconicQuebrada de HumahuacaArgentina · 140 km · 1-2 daysThis classic northwestern Argentina drive follows Ruta 9 through the Quebrada de Humahuaca, a narrow Andean valley of multicolored cliffs, adobe villages, and high-desert light. Start in San Salvador de Jujuy and end in Humahuaca, stopping at Purmamarca, Tilcara, and dramatic viewpoints along the UNESCO-listed corridor.